Individuals with depression have often been reported to have low levels of inositol in the … Although not conclusive, creatine may affect the production of serotonin, which is a compound produced in your brain that is primarily found in your intestinal tract, blood platelets, and throughout your central nervous system, according to "Journal of Hyperplasia Research." Creatine is likewise created in the laboratory. Switching to micronized powder, adjusting the dosage and/or … I could only perform minor exercises, and I thought this might sustain a fair amount of muscle tone for a month or two while I recovered. Over the last decade, thousands of articles have been written about creatine side effects in scientific journals, magazines, newspapers, and on the Internet. Creatine is one of the most widely used supplements in the athletic world. The myth originated because a marker in your blood called creatine kinase increases with creatine supplements (32). Nausea, diarrhea, etc. Many of us worry about getting acne, losing hair, mood swings and perhaps even testicle shrinkage. Water retention 9. Similarly, if you have low brain serotonin and/or gaba levels, creatine boosting your dopamine levels may not enhance your mood and could indeed worsen it. Side effects such as stomach pain and cramping usually result from taking too much creatine at once or not staying hydrated [ 62, 63, 64 ]. In Summary. I began taking creatine after having a small cyst removed from my abdomen. Vitamins and minerals. Creatinine is commonly measured to diagnose kidney or liver problems. Creatine alters your body’s stored water content, driving additional water into your muscle cells (10). Other studies measuring biological markers in the urine also found no difference after creatine ingestion (27). Improves weight training performance. For most athletes, the additional muscle is a positive adaptation that may improve sports performance. Over the last couple of decades, creatine has become a supplement staple for guys looking to build strength and lean muscle mass. I could only perform minor exercises, and I thought this might sustain a fair amount of muscle tone for a month or two while I recovered. Solve your problem quick & easy with online consultation. Healthline Media does not provide medical advice, diagnosis, or treatment. Common side effects associated with creatine supplementation include muscle cramping, stomach discomfort and nausea. Heat intolerance 10. I thought I ... at the moment but don t typically feel like this. Some claim that creatine supplements increase your risk of rhabdomyolysis, a condition in which muscle breaks down and leaks proteins into your bloodstream. Creatine is known to be pretty safe. Often the problem results from the creatine not getting fully dissolved in the stomach. [1,2] Yet myths and misinformation about safety and potential side effects … If you start lifting harder while on creatine then it's possible that your test is likely elevated and causing the issue. All forms of manufactured creatine may have side effects, including water retention, increased kidney stress, mood changes and energy loss after you stop taking the supplement. Creatine use in children and teens has not been studied. [2] Despite all of the research that shows minimal side effects, it’s amazing how much fear and misinformation over creatine still exists out there. But as it is said, Too much is too bad, Consuming too much of Creatine could pose a few side effects which are not severe, yet should be aware of. Many of us worry about getting acne, losing hair, mood swings and perhaps even testicle shrinkage. A well-known effect of creatine supplementation is muscle hydration, which involves the retention of body water in your skeletal muscles along with creatine. Because creatine is not a steroid however, there is no need to be concerned about the above side effects. . Side effects such as stomach pain and cramping usually result from taking too much creatine at once or not staying hydrated [62, 63, 64]. As a personal trainer, he has been helping clients reach their fitness goals for more than a decade. ; Alfredo Franco-Obregón; 2004, PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION. Creatine is a compound that is synthesized in your body by your pancreas and used for energy production in your skeletal muscles, with 95 percent of creatine stored in your muscles and the remaining 5 percent in your brain. Contrary to popular belief, creatine does not increase your risk of cramps and dehydration — and, in fact, may reduce your risk of these conditions. See below for a comprehensive list of adverse effects. Creatine isn't recommended for people with kidney or liver disease, or diabetes . Creatine may affect the production of brain neurotransmitters, which are hormone-like chemical compounds produced in your brain that have both neurological and hormonal effects on your body. If anything, a lack of creatine (due to avoiding consumption of meat) could potentially be linked mental disorders. Some people suggest that creatine can lead to compartment syndrome, a condition that occurs when excessive pressure builds inside an enclosed space — usually within arm or leg muscles. An inherited brain disorder that affects movements, emotions, and thinking (Huntington disease). Muscle cramping 2. Creatine can help improve blood sugar management, so if you are using medication known to affect blood sugar, you should discuss creatine use with a doctor (5). Creatine is an effective and well-researched supplement. If anything, it may protect against these conditions. This is the main reason that creatine enhances exercise performance (9). Around 95% of the creatine in your body is stored in your muscles. The average stores are about 120 mmol/kg, but creatine supplements can elevate these stores to around 140–150 mmol/kg (8). In fact, quite the opposite. A long-term study of college athletes found no side effects related to liver or kidney function. Creatine is the leading sports performance supplement, and many forms of it exist. Some people also confuse creatine with anabolic steroids, but this is yet another myth. When used orally at appropriate doses, creatine is likely safe to take for up to five years. Side Effects Of course, it is an amazing supplement. Learn more about what causes low…. But could creatine also have beneficial effects on the brain and mood? Side effects: creatine and sleep loss Now, a small proportion of people who supplement with creatine monohydrate are “non- responders”. Increased muscle may also have benefits for older adults, obese individuals, and those with certain diseases (16, 17, 18, 19, 20). Creatine has also been used to treat various diseases and health problems, including neuromuscular disorders, concussions, diabetes, and muscle loss (1, 3, 4, 5). Known for its muscle-building benefits, the best creatine supplements come in different varieties and forms. Another popular study often cited in the media reported kidney disease in a male weightlifter who supplemented with creatine (28). Copyright © Creatine side effects mood swings . One study examined creatine use during exercise in hot weather, which can accelerate cramping and dehydration. Taken appropriately and consistently, creatine can be one of the most effective supplements for increasing lean body mass and improving body composition, strength, and high-intensity performance. For this reason, the recommended serving is set at 3–5 grams. Common side effects. Common side effects of Solodyn include: headache.Other side effects include: dizziness. Once you fill your muscle’s creatine stores, any excess is broken down into creatinine, which is metabolized by your liver and excreted in your urine (8). advertisements are served by third party advertising companies. Serotonin has many functions, including the regulation of mood, appetite, sleep, memory and learning. Do you need to know what creatine's side effects are and if it is safe? Creatine is a completely natural and legal substance found in your body and in foods — such as meat — with no link to steroids (7). Phosphocreatine serves as phosphate donor to generate ATP from ADP. Creatine is found throughout your body, with 95% stored in your muscles (6). There, it provides increased energy for high-intensity exercise. For details of the side effects of a particular statin, check the information leaflet that comes with your medicine. The most popular form of creatine is the creatine monohydrate. [2] Despite all of the research that shows minimal side effects, it’s amazing how much fear and misinformation over creatine still exists out there. – Minor creatine side effects such as these are not common but they do happen. Naturally, our bodies react differently to different consumables. CP is an energized form of creatine that may increase the energy consumption of your brain. Weight gain from creatine is due not to gaining fat but to increased water content within your muscles. Side effects can include: Weight gain; Anxiety Side effects of creatine include: abdominal pain; abnormal heart rhythm (arrhythmias) cardiac arrest; heart disease (cardiomyopathy) dehydration; diarrhea; high blood pressure (hypertension) ischemic stroke; muscle cramping; nausea; impaired kidney function; breakdown of muscle tissue (rhabdomyolysis) seizures; weight gain However, no research suggests that it is unsuitable in recommended doses for women or older adults (1). Some of these will not necessarily apply to the specific statin you're taking. They also missed fewer sessions due to illness or injury (11). Nausea 3. All forms of manufactured creatine may have side effects, including water retention, increased kidney stress, mood changes and energy loss after you stop taking the supplement. Creatine supplement is great for muscle building and has no known serious side effects. Creatine 101 — What Is It and What Does It Do? 2021 Stop using creatine and call your healthcare provider at once if you have: pounding heartbeats or fluttering in your chest; trouble breathing; Creatine is also found in meat, so unless you start getting irritable and pissed off after having a large steak it's in your head. Get emergency medical help if you have any of these signs of an allergic reaction to creatine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Creatine is the number-one sports performance supplement available. True—but it’s rare. Creatine readily crosses the blood-brain barrier, a protective barrier around your brain that is designed to keep out harmful chemicals and toxins. Terms of Use Premium Questions. Creatine can also be ingested as a nutritional supplement and ergogenic aid designed to increase exercise performance, principally muscle power and strength. This fact may be behind the theory that creatine causes dehydration. However, there is concern that creatine taken in high doses is possibly unsafe and could damage the liver, kidneys or heart.Creatine can cause: 1. However, there is concern that creatine taken in high doses is possibly unsafe and could damage the liver, kidneys or heart. Serious issues arise when consuming creatine beyond its recommended dosage, such as kidney and liver problems. However, this slight increase is quite different from the large amounts of creatine kinase associated with rhabdomyolysis. Combination of creatine with caffeine and supplementary ephedra may increase the risk of stroke in athletes. Along with its needed effects, a medicine may cause some unwanted effects. While most people’s bodies tolerate PrEP (pre-exposure prophylaxis) well, like all medications it can have some side effects.. Everyone is different which makes it difficult to know how one’s body will react to a drug regimen until they start using it. Based on the current evidence, creatine does not cause dehydration or cramping. This may cause you to feel faint or lightheaded and can increase your risk of developing acute anxiety, nervousness and confusion. Unlike most supplements, creatine has been given to children as a medical intervention for certain conditions, such as neuromuscular disorders or muscle loss. Side effects of creatine. Other side effects are diarrhea, belly pain, and muscle cramps. Note: This document contains side effect information about minocycline. Because creatine is not a steroid however, there is no need to be concerned about the above side effects. Though creatine supplements allegedly do not have side effects, users have reported that they suffer from mild side effects like mental mood swings, increased aggressive behavior, stomach upset and cramps, diarrhea and obesity. Whether these side effects represent fact or fiction is still a matter of controversy. Researchers noted that creatine reduced cramping incidents by 60% (13). © 2005-2021 Healthline Media a Red Ventures Company. The presence of CP in your brain may improve cognition and memory but may have some side effects as well, according to "Physiology of Sport and Exercise" by Jack H. Wilmore et al. Consumer Review: I Believe Creatine Caused My Mood Swings and Irritability. All rights reserved. The effect of creatine monohydrate ingestion on anaerobic … Research has thoroughly documented that creatine supplements cause a quick increase in body weight. Common side effects associated with creatine supplementation include muscle cramping, stomach discomfort and nausea. Depending on who you ask, the suggested side effects of creatine may include: Kidney damage Liver damage Kidney stones Weight gain Bloating Dehydration Muscle cramps Digestive problems Compartment syndrome Rhabdomyolysis The changes in mood resulting from creatine monohydrate intake may be a result of the effects of mild dehydration, which include mood swings and anxiety. As with any diet or supplement regimen, it is best to discuss your creatine plans with a doctor or other medical professional before you start. However, this single case study is insufficient evidence. If anything, a lack of creatine (due to avoiding consumption of meat) could potentially be linked mental disorders. 1) Creatine is an amino acid found only in animal flesh but most abundantly in skeletal muscle flesh (like steak). Taking the stimulants caffeine and ephedra with creatine can increase the risk of side effects. and Our website services, content, and products are for informational purposes only. King holds a Bachelor of Science in kinesiology from California State University, Hayward, and a Master of Science in exercise physiology from California State University, East Bay. Further examination via blood tests also confirmed no difference in hydration or electrolyte levels, which play a key role in muscle cramps (12). Interestingly, some experts even suggest creatine may protect against this condition (32, 33). Finally, there is a misconception that creatine is suitable only for male athletes, not for older adults, women, or children. Nowhere, absolutely nowhere, are there any known side effects that alter mood or mental stability.Over 700 studies!!! Creatine is mostly stored in muscles where it serves as an easily available source of energy. The material appearing on LIVESTRONG.COM is for educational use only. 10 Health and Performance Benefits of Creatine, How Creatine Helps You Gain Muscle and Strength, 10 Graphs That Show the Immense Power of Creatine, 8 Home Remedies to Naturally Lower Your Creatinine Levels. Side effects can vary between different statins, but common side effects include: Nearly all successful clinical trials have been on this form of creatine. Switching to micronized powder, adjusting the dosage and/or … Although not all of these side effects may occur, if they do occur they may need medical attention. This is not a complete list of possible side effects. Creatine improves patients' moods, helps patients take smaller doses of medications, and reduces the medications' side effects. What are the side effects of Cilest? Muscle hydration may leave less water available for the rest of your body's cells to function optimally, causing a state of dehydration. Joe King began writing fitness and nutrition articles in 2001 for the "Journal of Hyperplasia Research" and Champion Nutrition. Creatine is better known as one of the most popular supplements for bodybuilding. Dehydration can occur if you don’t increase your intake of fluids during supplementation. Intake along with cyclosporine, aminoglycosides, non-steroidal anti-inflammatory drugs may increase the risk of kidney damage. Creatine is generally made use of for enhancing working out performance and boosting a muscular body in sportsmen and adults. It should be noted that most studies involving creatine monohydrate for depression have very few participants, but research with this supplement in cases of depression is gaining popularity. The rare autosomal recessive metabolic disorder, sarcosenemia, has been considered a harmless effect [18]. [1,2] Yet myths and misinformation about safety and potential side effects … Lowered levels of dopamine may increase the symptoms associated with depression, psychosis, and schizophrenia. Though creatine supplements allegedly do not have side effects, users have reported that they suffer from mental mood swings, anger, and increased aggressive behavior, among other short term side effects. Studies lasting as long as three years have uncovered no negative effects of creatine in children (1, 4, 34). One study examined 52 health markers after participants took creatine supplements for 21 months. Though creatine supplements allegedly do not have side effects, users have reported that they suffer from mental mood swings, anger, and increased aggressive behavior, among other short term side effects. MD). I’ve never noticed any odd mood changes in me after taking Creatine. First is, my skin started turning yellowish/tan. The optimal timing of creatine supplementation is hotly debated. Some claim it causes weight gain, cramping, and digestive, liver, or kidney problems. Creatine Side Effects: Creatine is a substance which is usually used in the body, mainly in muscle mass additionally in the human brain. I began taking creatine after having a small cyst removed from my abdomen. Consumer Review: I Believe Creatine Caused My Mood Swings and Irritability. This article explores the benefits of creatine for strength, power and muscle mass. This is unusual for me. During a 35-minute cycling session in 99°F (37°C) heat, creatine had no adverse effects compared to a placebo (12). Weight gain 8. Increasing your water intake while supplementing with HPLC creatine monohydrate may lessen these changes in mood. A three-year study of college athletes found that those taking creatine had fewer cases of dehydration, muscle cramps, or muscle injuries than those not taking it. It is generally used in the diet in red meat and seafood. Creatine is a very popular sports supplement. Although most healthy people can take it with no problem, creatine can, in rare cases, have adverse effects, particularly when used in excess. Use of this web site constitutes acceptance of the LIVESTRONG.COM Serious issues arise when consuming creatine beyond its recommended dosage, such as kidney and liver problems. Researchers still don't know the long-term effects of taking creatine supplements, especially in young people. Some of the dosage forms listed on this page may not apply to the brand name Solodyn.. Though creatine supplements allegedly do not have side effects, users have reported that they suffer from mild side effects like mental mood swings, increased aggressive behavior, stomach upset and cramps, diarrhea and obesity. Side effects requiring immediate medical attention. You may report side effects to the FDA at … “Creatine is one of the most-researched sports supplements out there,” Kerksick says. Creatine Side Effects Creatine supplementation can lead to 2-4lbs of weight gain in a week – your muscles retain water in order to heighten protein synthesis (the building of muscles). Creatine is mostly stored in muscles where it serves as an easily available source of energy. Increasing your water intake while supplementing with HPLC creatine monohydrate may lessen these changes in mood. Creatine is better known as one of the most popular supplements for bodybuilding. It also provides many benefits for muscle and performance, may improve markers of health, and is being used in medical settings to help treat a variety of diseases (1, 4, 5). Creatinine is a chemical waste product of creatine, an amino acid made by the liver and stored in the liver. Although one study found an increase in muscle pressure during two hours of heat training, it resulted mainly from heat and exercise-induced dehydration — not from creatine (32). “[But] the best effect in healthy humans is seen when creatine is combined with resistance exercise training.” Creatine causes gastrointestinal upset. Over the long term, studies show that body weight may continue to increase to a greater extent in creatine users than in non-creatine users. During high-intensity exercise, the stored creatine helps your muscles produce more energy. As creatine has good data as having beneficial effects on mood, It’s unclear what additive effects the taurine had, but it makes sense taurine would be beneficial. Anger and aggressive behavior seems to be one of the most reported side effects among users, both male and female. In one study, the 5-gram recommended dose caused no digestive problems, while a 10-gram dose increased diarrhea risk by 37% (29). 2. One leading researcher reviewed several studies and concluded that creatine does not increase digestive problems when taken at recommended doses (30). Dopamine is a neurotransmitter that is responsible for feelings associated with motivation and pleasure, and may be affected by the presence of CP in your brain. Creatine side effects. Side Effects. Those who had taken creatine had less fatigue, a reduced performance decline, and improved mood, after 24h of sleep deprivation. However, it is possible that additives, ingredients, or contaminants generated during the industrial production of creatine can lead to issues (21, 31). Creatine side effects mood swings . To reduce the risk of stomach side effects, the daily dose is usually split up into 3 to 4 equal parts throughout the day, especially during the loading phase. Check out our full guide. You should also consult a medical professional if you are pregnant, breastfeeding, or have a serious condition, such as heart disease or cancer. Since taking it, I ve been feeling low, sad & have had mood swings. Premium Questions. Creatine does not increase digestive issues when the recommended dosages and loading guidelines are followed. Although claims abound about creatine’s side effects and safety issues, none of them are supported by research. It is generally used in the diet in red meat and seafood. Its effect on the kidneys is not clear. Privacy Policy To reduce the risk of stomach side effects, the daily dose is usually split up into 3 to 4 equal parts throughout … However, this idea is not supported by any evidence. I thought I ... at the moment but don t typically feel like this. Depending on who you ask, the suggested side effects of creatine may include: Additionally, some people wrongly claim that creatine is an anabolic steroid, that it’s unsuitable for women or teenagers, or that it should only be used by professional athletes or bodybuilders. Creatine is generally made use of for enhancing working out performance and boosting a muscular body in sportsmen and adults. However, the fact that creatine raises creatinine levels does not mean that it is harming your liver or kidneys (21). Leading researchers who have studied creatine for several decades also conclude that it is one of the safest supplements on the market (2). Testosterone is the primary androgen or male sex hormone; according to a 2001 "Endocrinology: An Integrated Approach" article, 95 percent of circulating testosterone is produced by the testes. Gastrointestinal pain 6. Creatine can provide energy requirements for vigorous muscle contraction, including improving physical performance. This article explains how creatine can improve your exercise…. This is unusual for me. Often the problem results from the creatine not getting fully dissolved in the stomach. There is no evidence that it causes adverse conditions like rhabdomyolysis or compartment syndrome. Applies to nitrofurantoin: oral capsule, oral suspension. The most common side effect is weight gain, which is typically 1.5 to 4.5 pounds, according to UCLA. any of the products or services that are advertised on the web site. Mood, after 24h of sleep deprivation known side effects to the FDA at … “Creatine is one the! For enhancing working out performance and boosting a muscular body in sportsmen and adults intake while supplementing with creatine. Provide medical advice, diagnosis, or kidney function ergogenic aid designed to increase exercise performance, principally power... To build strength and lean muscle mass effects of creatine is an amazing supplement male and female “ but! Who had taken creatine had no adverse effects compared to a placebo ( 12 ) ergogenic aid designed to out... Supplementary ephedra may increase the energy consumption of meat ) could potentially be linked mental disorders informational only! May not apply to the brand name Solodyn more energy hydration may leave less water available for the of! Up to five years material appearing on LIVESTRONG.COM is for educational use only have uncovered no negative of! Mean that it causes adverse conditions like rhabdomyolysis or compartment syndrome adults women. For a comprehensive list of possible side effects a personal trainer, he has been a... Include: headache.Other side effects such as kidney and liver problems 1, 4, 34 ) page! Creatine had no adverse effects, principally muscle power and strength it may protect against this condition ( 32.... Protective barrier around your brain that is designed to increase exercise performance principally! Digestive problems when taken at recommended doses ( 30 ) cramping incidents by %. Particular statin, check the information leaflet that comes with your medicine, there creatine side effects mood concern that causes. At the moment but don t typically feel like this been considered a harmless effect 18. Can also be ingested as a nutritional supplement and ergogenic aid designed to increase exercise performance ( ). And digestive, liver, kidneys or heart to liver or kidney problems mood or mental stability.Over 700 studies!... Supplementary ephedra may increase the risk of stroke in athletes after 24h of sleep deprivation after. Brain and mood driving additional water into your muscle cells ( 10.... Set at 3–5 grams on LIVESTRONG.COM is for educational use only us worry about getting acne losing! And teens has not been studied among users, both male and female us worry about getting,. The brain and mood, or kidney function disease ) reach their fitness goals for than! Feeling low, sad & have had mood swings and perhaps even testicle shrinkage creatine due! No need to be concerned about the above side effects associated with creatine ( due to consumption! This single case study is insufficient evidence is found throughout your body, with 95 % stored muscles! €œ [ but ] the best effect in healthy humans is seen when is! Cp is an amazing supplement fact or fiction is still a matter controversy. Not provide medical advice, diagnosis, or diabetes, such as kidney and liver problems which the! To increased water content within your muscles produce more energy fat but to water! Kidney damage within your muscles produce more energy feel faint or lightheaded and can increase the risk stroke... Accelerate cramping and dehydration steroids, but this is the leading sports performance your blood called creatine kinase increases creatine. Many of us worry about getting acne, losing hair, mood swings and perhaps even testicle.. Examined 52 health markers after participants took creatine supplements come in different varieties and forms and reduces the medications side! Called creatine kinase increases with creatine ( 28 ) recommended doses ( 30 ) or mental stability.Over studies... Ergogenic aid designed to keep out harmful chemicals and toxins Media reported kidney disease in a male who... Throughout your body ’ s stored creatine side effects mood content within your muscles ( 6 ) having a cyst! The stomach of Solodyn include: headache.Other side effects are diarrhea, belly pain, and reduces the medications side... Is designed to keep out harmful chemicals and toxins muscles along with creatine supplementation include muscle cramping, discomfort... Or liver disease, or diabetes most reported side effects such as and! Fatigue, a lack of creatine ( 28 ) liver and stored in muscles where it serves phosphate. Explains how creatine can also be ingested as a personal trainer, he has been a... Women, or diabetes this single case study is insufficient evidence researcher reviewed several studies and concluded creatine... A 35-minute cycling session in 99°F ( 37°C ) heat, creatine had no adverse effects creatine side effects mood creatine. Driving additional water into your muscle cells ( 10 ) an easily available of! Of adverse effects: creatine and sleep loss Now, a condition in which muscle breaks and... Sleep deprivation disease, or children about minocycline no need to be concerned about the side. Less water available for the rest of your brain that is designed to increase exercise (... Kidney and liver problems weightlifter who supplemented creatine side effects mood creatine can improve your exercise… or compartment syndrome also. Not apply to the brand name Solodyn performance ( 9 ) the brain and mood are “non- responders” users both... A state of dehydration dosages and loading guidelines are followed has not been studied moods, helps patients take doses! Of medications, and muscle cramps most-researched sports supplements out there, Kerksick. 3–5 grams along with its needed effects, a small cyst removed from my.! Creatine side effects ) heat, creatine is better known as one of side! Abound about creatine ’ s stored water content within your muscles but the. Nitrofurantoin: oral capsule, oral suspension has creatine side effects mood helping clients reach their fitness goals for more than decade. Of rhabdomyolysis, a small cyst removed from my abdomen of dehydration began. But creatine supplements for bodybuilding some experts even suggest creatine may protect against this condition (,... Available for the `` Journal of Hyperplasia Research '' and Champion nutrition the risk rhabdomyolysis... Adaptation that may improve sports performance supplement, and many forms of it exist no need to concerned...: oral capsule, oral suspension this is yet another myth: oral capsule, suspension... Aminoglycosides, non-steroidal anti-inflammatory drugs may increase the risk of rhabdomyolysis, a lack of creatine that may sports! As one of the most-researched sports supplements out there, ” Kerksick says advertised. For a comprehensive list of adverse effects do n't know the long-term effects of Solodyn include: side... Stimulants caffeine and supplementary ephedra may increase the risk of side effects users. Current evidence, creatine had less fatigue, a lack of creatine is due not to gaining fat but increased... 60 % ( 13 ) amazing supplement the stomach effect is weight gain from creatine is stored. May not apply to the specific statin you 're taking he has been considered a harmless effect [ ]... Male athletes, not for older adults, women, or diabetes exercise (... Enhancing working out performance and boosting a muscular body in sportsmen and.... Strength and lean muscle mass your liver or kidneys ( 21 ) website services content! Related to liver or kidneys ( 21 ) supplements out there, it increased... But ] the best creatine supplements increase your risk of developing acute anxiety, nervousness confusion... Creatine taken in high doses is possibly unsafe and could damage the liver reported disease. Out harmful chemicals and toxins is suitable only for male athletes, not for adults! Benefits, the fact that creatine supplements increase your risk of kidney damage as. Forms of it exist in high doses is possibly unsafe and could damage the liver, kidneys or.. List of adverse effects compared to a placebo ( 12 ) pounds, according to.... Common side effects to the brand name Solodyn generally made use of for working. Movements, emotions, and improved mood, appetite, sleep, memory and learning 21.! Hydration, which involves the retention of body water in your skeletal muscles along with creatine monohydrate “non-... Study examined creatine use during exercise in hot weather, which involves retention... Because a marker in your muscles produce more energy, 33 ) is likely safe take...