Drug-drug interactions occur when two or more drugs react with each other, causing an unexpected side effect. It’s significant: For a small number of drugs, grapefruit’s effects can be serious. (7) 2. Keep an eye out for these unsafe combinations. Repaglinide (Prandin) is an example from the diabetes medication list that interacts with grapefruit products. Seville oranges, pomelos and tangelos can have the same effect on drugs as grapefruit, so best to avoid them if you know your drug can interact with grapefruit. Harmful interactions aren't limited to competing drugs you ingest; anything you put in your body can potentially alter a medication's effectiveness or cause other problems. According to the researchers, if you're taking medications … In addition, many medications can interact with other juices, such as orange, apple, and cranberry. This may include avoiding certain food-drug interactions, some of which involve fruits 3. Taking your medication a few hours apart from consuming it isn’t long enough. Different foods have adverse interactions with different medications. It’s important to take your antibiotic exactly as instructed. If you eat grapefruit or drink grapefruit juice at all, be aware that the fruit interacts with several classes of drugs, including statins (taken to … More than 85 medications are known to interact with grapefruit juice, and approximately one-half of these interactions have the potential to cause serious adverse events. Drugs that can react with orange, apple or grapefruit juice include some antibiotics, chemotherapy drugs and beta-blockers. If you're unsure about whether you can consume fruit or fruit juice with your medication… Do you enjoy grapefruit juice, frappuccinos or candy made from black licorice?If so, be sure to read your medication bottles. ... Do not take apple cider vinegar with these medications. Navel, Valencia and some other sweet oranges do not fall in this category. (6) 3 Examples of how Grapefruit Juice Effects Medications include: 1. ... bananas, bran, milk, oranges and carrots in your diet. Eating a nutritious diet and taking medications as prescribed by a doctor may seem like a recipe for good health, but even wholesome ingredients like leafy greens and fruit can cause food-drug interactions. For example, mixing a drug you take to help you sleep (a sedative) and a drug you take for allergies (an antihistamine) can slow your reactions and make driving a car or operating machinery dangerous. Here’s what you need to know about diet when you’re on a statin for high cholesterol. Opt for other fruits like kiwi fruit, blood oranges and other fresh produce instead, suggests Kennedy. When taken with medicine, grapefruit can delay, decrease, or enhance absorption of certain drugs; as a result, the patient does not receive the prescribed dosage of the medication. 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